Title: Activities of Lysyl oxidase (LOX) and Matrix metalloproteases in cultured Bovine Retinal Pigment epithelial cells-Role of Retinoic acid in their regulation.

Scope

•  To study the effect of oxidative stress and hyperglycemic effect on the expression of LOX.

•  To quantify the LOX in ocular tissue in normal and diseases condition.

Duration : Three years

Expected benefits : To understand the mechanism of LOX mediated alteration of extracellular matrix in ocular diseases.