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S. Barathi, M. Charanya, S. Muthukumaran, N. Angayarkanni and V. Umashankar. Comparative modeling of PON 2 and analysis of its substrate binding interactions using computational methods. Journal of Ocular Biology, Diseases, and Informatics. DOI: 10.1007/s12177-011-9057-7
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Selvi R, Angayarkanni N, Biswas J, Ramakrishnan S. Total antioxidant capacity in eales' disease compared to uveitis and cataract. IJMR 2011. (inpress)
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Barathi S. Angayarkanni N, Sumantran VN. GLUT-1 Expression in bovine retinal capillary endothelial cells and Pericytes exposed to Advanced Glycation End Products. . Invest Ophthalmol Vis Sci. 2010;51(12):6810-4.
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Sai Jyothi AV, Angayarkanni N, Syama C, Utpal T, Shweta A, Bhaskar S, Geetha IK, Vinay PS, Thennarasu M, Sivakumar RM, Prema P. Two Dimension Electrophoretic analysis of Human tears: Collection method in Dry Eye Syndrome, Electrophoresis 2010, 31:3420–7
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Verma A, Biswas J, Selvi R and Angayarkanni N. Intra-ocular expression of vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) in a case of Eales’ disease by immunohistochemical analysis: a case report. Int. Ophthalmology. Published online: 5 January 2010
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Selvi R, Angayarkanni N, Asma B, Seethalakshmi T, Vidhya S. Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions. Mol. Cell. Biochem. 2010;344(1-2):43-53.
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Barathi S, Angayarkanni N, Aarthi P, Sulochana KN, Rishi P, Maneesh D, Velpandian T, Charanya, M, Muthukumaran S. Homocysteinethiolactone and Paraoxonase - novel markers of Diabetic Retinopathy. Diabetes Care, published online June 14, 2010
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Angayarkanni N, Selvi R, Pukraj R, Biswas J, Bhavesh SJ, Tink JT. Ratio of the Vitreous Vascular Endothelial Growth Factor and Pigment Epithelial-Derived Factor in Eales Disease. Journal of Ocular Biology, Diseases and Informatics. 2009;2(1): 20-28
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Sai Jyothi AV, Angayarkanni N, Vidhya S, Geetha KI, Ramakrishnan S, Subramanian M, Rajeshwari M. Tear ascorbic acid levels and the total antioxidant status in contact lens wearers. Indian J. Ophthalmol. 2009;57:289-92.
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Jayachandran VV, Angayarkanni N, Coral K et al., Diffusion of lidocaine buffered to an optimal pH across the endotracheal tube cuff – an in vitro studies Indian J. Anaesth. 2008;52(5):536-40.
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Coral K, Angayarkanni N, Gomathy N, Bharathselvi M, Pukhraj R, Rupak R. Homocysteine levels in vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment- its modulating role on lysyl oxidase activity . Invest Ophthalmol Vis Sci. 2009 Apr 15
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Coral K, Narayanasamy A, Madhavan J, Bharathselvi M, Ramakrishnan S, Nandi K, Rishi P, Kasinathan N, Krishnakumar S. Lysyl oxidase (LOX) activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment. Invest Ophthalmol Vis Sci. 2008;49:4746-52.
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Angayarkanni N, Barathi S, Seethalakshmi T, Punitham R, Ramakrishnan S, Tarun S. Serum PON1 Arylesterase activity in relation to Hyperhomocysteinemia and Oxidative stress in young adult Central Retinal Venous Occlusion patients. Eye 2008;22(7):969-74.
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Madhavan J, Coral K, Mallikarjuna K, Corson TW, Amit N, Khetan V, George R, Biswas J, Gallie BL, Kumaramanickavel G. High Expression of KIF14 in Retinoblastoma: Association with Older Age at Diagnosis. KIF14. Invest Ophthalmol Vis Sci. 2007;48:4901-6.
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Selvi R, Thomas A, Angayarkanni N, Bharathselvi M, Biswas J, Vasanthi SB, Ramakrishnan S, Tarun Sharma, S.B. Vasanthi. Increase in Fe3+/Fe2+ ratio and iron-induced oxidative stress in Eales’ disease and presence of ferrous iron in circulating transferring. Curr. Eye Res. 2007;32:677-83.
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Barathi S, Vadhana P, N Angayarkanni, S Ramakrishnan. Estimation of Hydrogen sulphide in the human lymphocytes. Ind. J. Biochem. Biophys, 2007;44:179-82.
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Ramakrishnan S, Rajesh M, Sulochana KN. Eales’ disease: Oxidant stress and weak antioxidant defence. Ind. J.Ophthalmol. 2007;55: (2):95-102.
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Angayarkanni N, Barathi S, Coral K, Punitham R, Ramakrishnan S, Tarun Sharma, S.B. Vasanthi. Hyperhomocysteinemia, as well as low methionine stress are risk factors for central retinal vascular occlusion in India population. IOVS. 2007;48:1441-6.
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Nishanthi M, Coral K, Angayarkanni N, Ramakrishnan S. Estimation of Taurine and its relevance in retina. Insight 2007;XXV(1):6-9
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BOOKS / CHAPTERS IN BOOKS PUBLISHED
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Sulochana KN, Coral K. Extra cellular matrix protein, Lysyl oxidase, as a therapeutic target for ocular angiogenesis” In: Advances in Medicine and Biology. Vol.1(Chapter 15) Editor: Leon V. Berhardt. 2009 Nova Science Publishers, Inc
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Ramakrishnan S, Rajesh M, Sulochan KN. A Novel 88 kDa acute phase protein in inflammation and its antioxidant fraction. Focus on Eye Research, Nova Science Publishers, Inc. NY. 2005
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Ramakrishnan S, N Angayarkanni, Basics In Biochemistry For Professional Nursing BI Publication, Chennai, 2006.
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Dr. S. Ramakrishnan et al Tamil book -Textbook of Medical Biochemistry; Tanjavur University, 2002.
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Dr. S. Ramakrishnan, Prasannan KG, Rajan R. Textbook of Medical Biochemistry for MBBS students under the aegis of National Book Trust, Government of India, through M/S Orient Longman Ltd., Chennai. 3 ed: 2002.
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Dr. S. Ramakrishnan et al Multiple choice questions in Biochemistry T.R. Publications, Chennai.
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Dr. S. Ramakrishnan. Biochemistry-Students manual-T.R. Publications, Chennai. 1st edn. 1994.
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Dr. S. Ramakrishnan, Raji Swami. Text Book of clinical (Medical) Biochemistry and Immunology, T.R. publications, Chennai. 1995.
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Dr. S. Ramakrishnan, Venkat Rao S. Nutritional Biochemistry TR publications, Chennai. 1st edn. 1995.
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Dr. S. Ramakrishnan. Essentials of Biochemistry & Ocular Biochemistry. 1st edn, Annamalai University Publications 1992.
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Dr. S. Ramakrishnan, Rajagopal G Practical Biochemistry for Medical Students. 1st edn, Orient Longman, Calcutta, 1983.
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Dr. S. Ramakrishnan, Medical Laboratory Technology Vol. 3, Ed. Kannai Mukherjee, Maryland, USA.
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Dr. S. Ramakrishnan, Topics in Biochemistry for BDS, B.Sc. Nursing and M.Sc. Zoology, Annamalai University Publications.
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Dr. S. Ramakrishnan, Organic Chemistry and Bio-Physics for Medical Students (M/s. Nagiah Chetty & Sons, Publishers Chennai) 1985
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Book under preparation: Manual of Medical Laboratory techniques, JAYPEE BROTHERS MEDICAL PUBLISHERS (P) LTD. |
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PUBLICATIONS CATAGORIZED IN DISEASES OR CONDITIONS
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S. Ramakrishnan, K.N. Sulochana. Decrease in glycation of lens proteins by lysine and glycine by scavenging of glucose and possible mitigation of cataractogenesis. Exp. Eye Res. 57:623-628;1993.
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S. Ramakrishnan, K. N. Sulochana, R. Punitham, K. Arunagiri. Free alanine, aspartic acid, or glutamic acid reduce the glycation of human lens proteins. Glycocon J 13:519-523;1996.
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S. Ramakrishnan, K.N. Sulochana, R. Punitham. Free lysine, glycine, alanine, glutamic acid and aspartic acid reduce the glycation of human lens proteins by galactose. Indian J Biochem Biophys 34:518-523;1997.
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K.N. Sulochana, R. Punitham, S. Ramakrishnan. Beneficial effect of lysine and amino acids on cataractogenesis in experimental diabetes through possible antiglycation of lens proteins. Exp Eye Res 67: 597-601; 1998.
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K.N. Sulochana, S. Ramakrishnan, M. Rajesh, K. Coral, S.S. Badrinath. Diabetic retinopathy: Molecular Mechanisms, present regime of treatment and future perspectives. Current Science 80(2):133-142;2001.
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K.N. Sulochana, M. Rajesh, S. Ramakrishnan. Insulin Receptor Tyrosine Kinase Activity in monocytes of Type 2 Diabetes Mellitus Patients receiving oral L-Lysine. Indian J Biochem Biophys. 38: 331-334;2001
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K.N. Sulochana, C. Indra, M. Rajesh, V. Srinivasan, S. Ramakrishnan Beneficial effects of amino acids in mitigating cytoskeletal actin glycation and improving F-actin content: In vitro. Glycoconjugated Journal 18(4): 277-282;2001.
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K.N. Sulochana, S. Lakshmi, R. Punitham, T. Arokiasamy, B. Sukumar,
S. Ramakrishnan. Effect of oral supplementation of free amino acids in type 2 diabetic patients - a pilot clinical trial. Med. Sci. Monit. 8(3):CR131-137;2002.
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Sulochana KN, Ramprasad S, Coral K, Lakshmi S, Punitham R. Angayarkanni N, Ramakrishnan S. Glycation and glycoxidation studies on the isolated human vitreous collagen: in vitro. Med Sci Monit. 2003; 9(6):BR220-224.
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Ramakrishnan S, Sulochana KN, Rajesh M, Lakshmi S, Coral K., Punitham R. Beneficial effect of oral supplementation of lysine or amino acids mixture in cataractogenesis, control of diabetes and diabetic retinopathy. National Academy of Medical Science India. 2002;38:75-92.
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Srinivasan V, Rajesh M, Sulochana1 KN, Indra C, S Ramakrishnan. Amino acids differentially regulate insulin receptor tyrosine kinase and phosphatidyl inositol-3-OH-kinase activities in human monocytes exposed to high glucose concentration. Indian J Bioche Biophys 42:2005.
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Barathi S, Angayarkanni N, Aarthi P, Sulochana KN, Rishi P, Maneesh D, Velpandian T, Charanya, M, Muthukumaran S. Homocysteinethiolactone and Paraoxonase - novel markers of Diabetic Retinopathy. Diabetes Care Publish Ahead of Print, published online June 14, 2010.
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Selvi R, Angayarkanni N, Asma B, Seethalakshmi T, Vidhya S. Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions. Mol. Cell. Biochem. 2010;344(1-2):43-53.
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S. Ramakrishnan, K. N. Sulochana, T. Selvaraj, A. Abdul Rahim, M. Lakshmi,
K. Arunagiri. Smoking of beedies and cataract: cadmium and vitamin C in the lens and blood. Br J Ophthalmol 79: 202-206; 1995.
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Cigarettes and cataract cadmium or a lack of vitamin C? Br J Ophthalmol (Editorial) 79: 199-201; 1995.
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K. N. Sulochana, S. Ramakrishnan, R. Punitham, Biju Joseph. Cadmium and superoxide dismutase in tobacco chewers with cataract. (Letters to the Editor) Indian J Pharmacol 30:413;1998.
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K.N. Sulochana. Smoking Cataract (Correspondence: Letters to the Editor) Current Science 81(9):101;2001.
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K. N. Sulochana, R. Punitham, S. Ramakrishnan. Oral supplementation of Zinc promotes erythrocyte superoxide dismutase activity in chronic cigarette smokers - report on a pilot clinic trial. (Letter to the Editor) Indian J Pharmacol 33;2001.
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K. N. Sulochana, R. Punitham, S. Ramakrishnan. Effect of cigarette smoking on cataract: antioxidant enzymes and constitutent minerals in the lens and blood of human. Indian J. Pharmacol. 34:428-431;2002.
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K. N. Sulochana, S. Ramakrishnan, K. Arunagiri. Purification and characterization of a new enzyme dipeptidase from human lens. Exp. Eye. Res.62:221-229;1996.
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K. N. Sulochana, S. Ramakrishnan, R. Punitham. Increased lens dipeptidase activity in aging and Cataract, Scientific correspondence. (Mailbox) Br J. Ophthalmol 83:885-7;1999.
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S. Ramakrishnan, K. N. Sulochana, R. Punitham, Bibhas Kar, K. Ravishankar, S.B. Vasanthi, Prema Lakshminarayanan. Pregnancy-exaggerated galactosemia and congenital cataracts. Indian J Pediatr 65:919-924;1998.
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K.N. Sulochana, S. Ramakrishnan, S.B. Vasanthi, H.N. Madhavan, K. Arunagiri, R. Punitham. First report of congenital or infantile cataract in deranged metabolism with released xylose. Br J Ophthalmol 81:319-323;1997
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K.N. Sulochana, S. Ramakrishnan, S.B. Vasanthi, H.N. Madhavan, K. Arunagiri, R. Punitham. Association of GAG fragments and Xylose with Congenital Cataract. Ophthalmology Digest 29-30;1998.
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K.N. Sulochana, S. Amirthalakshmi, S.B. Vasanthi, S. Ramakrishnan. Homocystine with congenital and developmental cataract, Probable Mechanism and Desirable Therapeutic Approach. Indian J Pediatr 67(10):725-728;2000.
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V. Bhooma, K. N. Sulochana, J. Biswas, S. Ramakrishnan. Eales' disease: accumulation of reactive oxygen intermediated and lipid peroxides and decrease of antioxidants causing inflammation, neovascularization and retinal damage. Curr. Eye Res 16:91-95;1997.
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K.N. Sulochana, J. Biswas, S. Ramakrishnan. Eales' disease: increased oxidation and peroxidation products of membrane constituent's chiefly lipids and decreased antioxidant enzymes and reduced glutathione in vitreous. Curr. Eye. Res. 19(3):254-259; 1999.
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K.N. Sulochana, M. Rajesh, S. Ramakrishnan. Purification and characterization of an 88 kDa novel protein from patients with Eales disease. Exp. Eye Res. 73:547-555;2001.
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M. Swamy, K. Coral, S. Krishnakumar, J. Biswas, S. Ramakrishnan, RH. Nagaraj, K.N. Sulochana. Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: A possible role in ocular neovascularization. Curr. Eye Res. 24(6):2002.
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Rajesh M, Sulochana KN, Amirthalakshmi S, Krishnakumar S, Biswas J,
Ramakrishnan S. Presence of a 88 kDa eales protein in uveitis, tuberculosis, leprosy and rheumatoid arthritis. Med Sci Monit. 2003; 9(1):CR95-99.
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Rajesh M, Ramesh A, Ravi PE, Balakrishnamurthy P, Coral K, Punitham R, Sulochana KN, Biswas J, Ramakrishnan S. Accumulation of 8 Hydroxydeoxyguanosine and its Relationship with Antioxidant Parameters in patients with Eales’ disease: Implications for Antioxidant Therapy. Current Eye Research 27 (2): 103-110; 2003.
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Rajesh M, Sulochana KN, Punitham R. Lakshmi S, Ramakrishnan S. Involvement of oxidative and nitrosative stress in promoting retinal vacuities in patients with Eales’ disease. Clinical Biochemistry. 36(5): 377-385;2003.
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Rajesh M, Sulochana KN, Coral K, Punitham R, Biswas J, Babu K, S. Ramakrishnan. Determination of Carbonyl Groups Content in Plasma Proteins as a useful Marker for Assessing the Impairment in Antioxidant Defense in Patients' with Eales' Disease. Indian Journal of Ophthalmology. 2004;52:139-144.
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Rajesh M, Sulochana KN, Ramakrishnan S, Biswas J, Manoharan PT. Iron Chelation Abrogates Excessive Formation of Hydroxyl Radicals and Lipid Peroxidation Products in Monocytes of Patients' with Eales' Disease: Direct Evidence using Electron Spin Resonance Spectroscopy. Current Eye Research 2004;28(6):399-407.
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Ramakrishnan S, Rajesh M, Sulochana KN. Eales’ disease: Oxidant stress and weak antioxidant defence. Ind. J.Ophthalmol. 2007;55: (2):95-102.
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Selvi R, Thomas A, Angayarkanni N, Bharathselvi M, Biswas J, Vasanthi SB, Ramakrishnan S, Tarun Sharma, S.B. Vasanthi. Increase in Fe3+/Fe2+ ratio and iron-induced oxidative stress in Eales’ disease and presence of ferrous iron in circulating transferring. Current Eye Research 2007. (inpress).
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Angayarkanni N, Selvi R, Pukraj R, Biswas J, Bhavesh SJ, Tink JT. Ratio of the Vitreous Vascular Endothelial Growth Factor and Pigment Epithelial-Derived Factor in Eales Disease. Journal of Ocular Biology, Diseases and Informatics. 2009;2(1): 20-28.
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Verma A, Biswas J, Selvi R and Angayarkanni N. Intra-ocular expression of vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) in a case of Eales’ disease by immunohistochemical analysis: a case report. Int. Ophthalmology. Published online: 5 January 2010
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Selvi R, Angayarkanni N, Biswas J, Ramakrishnan S. Total antioxidant capacity in Eales' disease compared to uveitis and cataract. IJMR 2011. (inpress)
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Barathi S. Angayarkanni N, Sumantran VN. GLUT-1 Expression in bovine retinal capillary endothelial cells and Pericytes exposed to Advanced Glycation End Products. . Invest Ophthalmol Vis Sci. 2010;51(12):6810-4.
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| |
Selvi R, Angayarkanni N, Asma B, Seethalakshmi T, Vidhya S. Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions. Mol. Cell. Biochem. 2010;344(1-2):43-53.
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| |
| |
S. Barathi, M. Charanya, S. Muthukumaran, N. Angayarkanni and V. Umashankar. Comparative modeling of PON 2 and analysis of its substrate binding interactions using computational methods . Journal of Ocular Biology, Diseases, and Informatics. DOI: 10.1007/s12177-011-9057-7
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K.N. Sulochana, S. Ramakrishnan, M. Lakshmi, R. Punitham. Possible role of polyamines in gyrate atrophy. Indian J Ophthalmol 48: 37-43; 2000.
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Deepa G Raj, S. Ramakrishnan, C.S. Shyamala Devi. Myoinositol and peroxidation – An in vitro study on human cataractous lens and human erythrocytes. Indian J Biochem. Biophys. 32:109-111;1995.
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S. Ramakrishnan, K. N. Sulochana, R. Punitham. Two new functions of inositol in the eye lens: Antioxidation and antiglycation and possible mechanisms. Indian J Biochem Biophys 36:129-133;1999.
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S. Ramakrishnan, K.N. Sulochana, Sunil Parikh, R. Punitham. Transthyretin (prealbumin) in Eye Structures and Variation of Vitreous Transthyretin in Diseases. Indian J Opthalmol, 47:31-34;1999.
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HPLC technique for analysis of antibiotics in aqueous humor
K. N. Sulochana, V. Bhooma, H.N. Madhavan, S. Ramakrishnan, A. Biswas. High performance liquid chromatographic method for simultaneous determination of ampicillin and sulbactam in biological samples. Indian J Pharmacol 27:189-192;1995.
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Dipeptidase enzyme
K. N. Sulochana, S. Ramakrishnan, K. Arunagiri. Purification and characterization of a new enzyme dipeptidase from human lens. Exp. Eye. Res 62:221-229;1996.
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Sai Jyothi AV, Angayarkanni N, Syama C, Utpal T, Shweta A, Bhaskar S, Geetha IK, Vinay PS, Thennarasu M, Sivakumar RM, Prema P. Two Dimension Electrophoretic analysis of Human tears: Collection method in Dry Eye Syndrome", Electrophoresis 2010, 31, 3420–7
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Sulochana KN, Coral K, Punitham R, Tarun Sharma, Kasinathan N, S. Ramakrishnan. Trace elements Iron, Copper and Zinc in vitreous of patients with various vitreoretinal diseases. Indian Journal of Ophthalmology. 2004;52:145-148.
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K Coral, R Raman, Rathi S, Rajesha M, Sulochana KN, Angayarkanni N, Paul PG, Ramakrishnana S. Plasma Homocysteine and Total Thiol Content in patients with Exudative Age Related Macular Degeneration. Eye 2006;20:203–7.
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Ramakrishnan S, Sulochana KN, Lakshmi S, Selvi R, Angayarkanni N. Biochemistry of homocysteine in health and diseases. Ind. J. Biochem. Biophys, 2006;43:275-83.
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Angayarkanni N, Barathi S, Coral K, Punitham R, Ramakrishnan S, Sharma T, S.B. Vasanthi. Hyperhomocysteinemia, as well as low methionine stress are risk factors for central retinal vascular occlusion in India population. IOVS. 2007;48:1441-6.
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Barathi S, Vadhana P, N Angayarkanni, S Ramakrishnan. Estimation of Hydrogen sulphide in the human lymphocytes. Ind. J. Biochem. Biophys, 2007;44:179-82.
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