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Sankara Nethralaya
Sankara Nethralaya
Back to Biochemistry
Department of Biochemistry and Cell Biology
Sivagurunathan S, Palanisamy K, Arunachalam JP, Chidambaram S. Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway. Molecular and cellular biochemistry. 2017;427(1-2):145-56. Epub 2016/12/28.
Ramanujam S, Muthuvel B, Aravind CB, Biswas J, Konerirajapuram NS. The 88-kDa Eales' protein in serum is a complex of haptoglobin, complement C3, and galectin-1 as identified by liquid chromatography coupled mass spectrometry. Proteomics Clinical applications. 2017;11(1-2) Epub 2016/10/16.
Muralikumar S, Vetrivel U, Narayanasamy A, U ND. Probing the intermolecular interactions of PPARgamma-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. Lipids in health and disease. 2017;16(1):17. Epub 2017/01/23.
Aluru SV, Shweta A, Bhaskar S, Geetha K, Sivakumar RM, Utpal T, et al. Tear Fluid Protein Changes in Dry Eye Syndrome Associated with Rheumatoid Arthritis: A Proteomic Approach. The ocular surface. 2017;15(1):112-29. Epub 2016/10/30.
Indhushree RM, K Coral, N Angayarkanni, R Punitham, BM Subburathinam, R Krishnakumar, PP Santanam. Visual functions of workers exposed to organic solvents in petrochemical industries. Indian Journal of Occupational & Environmental Medicine. 2016;20:133-7.
Gomathy Narayanan I, Saravanan R, Bharathselvi M, Biswas J, Sulochana KN. Localization of Human Copper Transporter 1 in the Eye and its Role in Eales Disease. Ocular immunology and inflammation. 2016;24(6):678-83. Epub 2016/01/26.
Gayathri R, Coral K, Sharmila F, Sripriya S, Sripriya K, Manish P, et al. Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ss Levels and LOXL1 Genotype in Pseudoexfoliation. Current eye research. 2016;41(10):1331-8. Epub 2016/04/27.
Bharathselvi M, Biswas S, Raman R, Selvi R, Coral K, Narayanansamy A, et al. Homocysteine & its metabolite homocysteine-thiolactone & deficiency of copper in patients with age related macular degeneration - A pilot study. The Indian journal of medical research. 2016;143(6):756-62. Epub 2016/10/18.
Bharathi Devi SR, Dhivya MA, Sulochana KN. Copper transporters and chaperones: Their function on angiogenesis and cellular signalling. Journal of biosciences. 2016;41(3):487-96. Epub 2016/09/02.
AnandBabu K, Bharathidevi SR, Sripriya S, Sen P, Prakash VJ, Bindu A, et al. Serum Paraoxonase activity in relation to lipid profile in Age-related Macular Degeneration patients. Experimental eye research. 2016;152:100-12. Epub 2016/10/04.
Srinivasan V, Sulochana KN. Effect of adiponectin on expression of vascular endothelial growth factor and pigment epithelium-derived factor: an in vitro study. Indian journal of pharmacology. 2015;47(1):117-20. Epub 2015/03/31.
Sivasankar S, Lavanya R, Brindha P, Angayarkanni N. Aqueous and alcoholic extracts of Triphala and their active compounds chebulagic acid and chebulinic acid prevented epithelial to mesenchymal transition in retinal pigment epithelial cells, by inhibiting SMAD-3 phosphorylation. PloS one. 2015;10(3):e0120512. Epub 2015/03/21.
M Bharathselvi SV, Pukhraj R, KN Sulochana. Increased Vitreous Heme oxygenase activity is associated with Proliferative diabetic Retinopathy. Indian journal of Clinical Biochemistry.
Kaviarasan K, Jithu M, Arif Mulla M, Sharma T, Sivasankar S, Das UN, et al. Low blood and vitreal BDNF, LXA4 and altered Th1/Th2 cytokine balance are potential risk factors for diabetic
retinopathy. Metabolism: clinical and experimental. 2015;64(9):958-66. Epub 2015/05/26.
Gomathy N, Sumantran VN, Shabna A, Sulochana KN. Tolerance of ARPE 19 cells to organophosphorus pesticide chlorpyrifos is limited to concentration and time of exposure.
Pesticide biochemistry and physiology. 2015;117:24-30. Epub 2015/01/27.
Bharathi Devi SR CK, Sulochana KN, Angayarkanni N. Free Amino Acids Glycine and Glutamic Acid Inhibit Angiogenesis Induced by AGE in Bovine Retinal Endothelial Cells. J Glycomics Lipidomics. 2015;5:2.
Vidhya S KP, Coral K, Subbulakshmi C, PukhrajR, Sulochana KN. Expression and localisation of adiponectin and its receptors in human ocular tissues. 2014 [cited 5(1)]; 639-46].
Mohankumar A, Renganathan B, Karunakaran C, Chidambaram S, Konerirajapuram Natarajan S. Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study. Journal of peptide science : an official publication of the European Peptide Society. 2014;20(11):837-49. Epub 2014/07/22.
Jasna JM, Anandbabu K, Bharathi SR, Angayarkanni N. Paraoxonase enzyme protects retinal pigment epithelium from chlorpyrifos insult. PloS one. 2014;9(6):e101380. Epub 2014/07/01.
Bhuvanasundar R, John A, Sulochana KN, Coral K, Deepa PR, Umashankar V. A molecular model of human Lysyl Oxidase (LOX) with optimal copper orientation in the catalytic cavity for induced fit docking studies with potential modulators. Bioinformation. 2014;10(7):406-12. Epub 2014/09/05.
Arun M B, K Coral, Sulochana KN. Peptide derived from n-terminal of lysyl oxidase promote endothelial attachment and migration by inducing enzymatic activity. Int J Pharm Bio Sci
Arora B, Narayanasamy A, Nirmal J, Halder N, Patnaik S, Ravi AK, et al. Development and validation of a LC-MS/MS method for homocysteine thiolactone in plasma and evaluation of its
stability in plasma samples. Journal of chromatography B, Analytical technologies in the biomedical and life sciences. 2014;944:49-54. Epub 2013/12/03.
Agarwal S, Angayarkanni N, Iyer G, Srinivasan B, Natarajan R, Charola S, et al. Clinico- biochemical correlation of the effect of subconjunctival bevacizumab for corneal neovascularization. Cornea. 2014;33(10):1016-21. Epub 2014/08/05.
Vidhya S SC, K Coral, P Rishi, KN Sulochana. Measurement of adiponectin in vitreous and plasma of patients with proliferative diabetic retinopathy and its correlation with vascular endothelial growth factor, pigment epithelial derived factor and insulin like growth factor-1. Int J Pharm Bio Sci. 2013;4(1):993-1005.
Vandhana S, Coral K, Jayanthi U, Deepa PR, Krishnakumar S. Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. Biochimica et biophysica acta. 2013;1831(9):1458-66. Epub 2013/07/03.
Narayanan G, R BS, Vuyyuru H, Muthuvel B, Konerirajapuram Natrajan S. CTR1 silencing inhibits angiogenesis by limiting copper entry into endothelial cells. PloS one. 2013;8(9):e71982. Epub 2013/09/17.
Muthukumaran S AK, Sulochana KN, Umashankar V. Elucidation of iron binding patterns through insilico approaches in human iron binding proteins. International Journal of Therapeutic Applications. 2013;10:11-8.
Coral K, Madhavan J, Pukhraj R, Angayarkanni N. High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells. Current eye research. 2013;38(1):194-203. Epub 2012/09/13.
Biswas J, Ravi RK, Naryanasamy A, Kulandai LT, Madhavan HN. Eales' disease - current concepts in diagnosis and management. Journal of ophthalmic inflammation and infection. 2013;3(1):11. Epub 2013/03/22.
Bharathselvi M, Biswas J, Selvi R, Coral K, Narayanasamy A, Ramakrishnan S, et al. Increased homocysteine, homocysteine-thiolactone, protein homocysteinylation and oxidative stress in the circulation of patients with Eales' disease. Annals of clinical biochemistry. 2013;50(Pt 4):330-8. Epub 2013/06/14.
Vetrivel U, Ravichandran SB, Kuppan K, Mohanlal J, Das UN, Narayanasamy A. Agonistic effect of polyunsaturated fatty acids (PUFAs) and its metabolites on brain-derived neurotrophic factor (BDNF) through molecular docking simulation. Lipids in health and disease. 2012;11:109. Epub 2012/09/05.
Selvi R, Bhuvanasundar R, Saijyothi AV, Sulochana KN, Angayarkanni N. Amino acids potentiate insulin signaling in CHO-K1 at high glucose conditions. Archives of medical research.
2012;43(3):173-82. Epub 2012/05/23.
Saijyothi AV, Fowjana J, Madhumathi S, Rajeshwari M, Thennarasu M, Prema P, et al. Tear fluid small molecular antioxidants profiling shows lowered glutathione in keratoconus. Experimental eye research. 2012;103:41-6. Epub 2012/09/11.
Ramakrishnan S SR, Saijyothi AV, Biswas J, Bharathselvi M, Angayarkanni N. Clinical and biochemical effects in patients with Eales disease on oral supplementation of antioxidant vitamins E and C. Biomedicine. 2012;2012(32(2)):162-8.
Mathangi J SN, Vidya N, Umashankar V, Sulochana K.N. Elucidation of structure - function relationship in families of copper binding proteins in homo sapiens – a bioinformatics approach. Int J Pharm Bio Sci. 2012;3(3):647-62.
Bharathi Devi SR, Suganeswari G, Sharma T, Thennarasu M, Angayarkanni N. Homocysteine induces oxidative stress in young adult central retinal vein occlusion. The British journal of ophthalmology. 2012;96(8):1122-6. Epub 2012/05/26.
Aluru SV, Agarwal S, Srinivasan B, Iyer GK, Rajappa SM, Tatu U, et al. Lacrimal proline rich 4 (LPRR4) protein in the tear fluid is a potential biomarker of dry eye syndrome. PloS one.
2012;7(12):e51979. Epub 2012/12/29.
Selvi R, Angayarkanni N, Biswas J, Ramakrishnan S. Total antioxidant capacity in Eales' disease, uveitis & cataract. The Indian journal of medical research. 2011;134:83-90. Epub 2011/08/03.
Verma A, Biswas J, Radhakrishnan S, Narayanasamy A. Intra-ocular expression of vascular endothelial growth factor (VEGF) and pigment epithelial-derived factor (PEDF) in a case of Eales' disease by immunohistochemical analysis: a case report. International ophthalmology. 2010;30(4):429-34. Epub 2010/01/06.
Selvi R, Angayarkanni N, Asma B, Seethalakshmi T, Vidhya S. Amino acids influence the glucose uptake through GLUT4 in CHO-K1 cells under high glucose conditions. Molecular and cellular biochemistry. 2010;344(1-2):43-53. Epub 2010/07/16.
Saijyothi AV, Angayarkanni N, Syama C, Utpal T, Shweta A, Bhaskar S, et al. Two dimensional electrophoretic analysis of human tears: collection method in dry eye syndrome. Electrophoresis. 2010;31(20):3420-7. Epub 2010/10/01.
Barathi S, Charanya M, Muthukumaran S, Angayarkanni N, Umashankar V. Comparative modeling of PON2 and analysis of its substrate binding interactions using computational methods. Journal of ocular biology, diseases, and informatics. 2010;3(2):64-72. Epub 2010/06/01.
Barathi S, Angayarkanni N, Sumantran VN. GLUT-1 expression in bovine retinal capillary endothelial cells and pericytes exposed to advanced glycation end products. Investigative ophthalmology & visual science. 2010;51(12):6810-4. Epub 2010/08/13.
Barathi S, Angayarkanni N, Pasupathi A, Natarajan SK, Pukraj R, Dhupper M, et al. Homocysteinethiolactone and paraoxonase: novel markers of diabetic retinopathy. Diabetes care. 2010;33(9):2031-7. Epub 2010/06/17.
Venkata SJ, Narayanasamy A, Srinivasan V, Iyer GK, Sivaramakrishnan R, Subramanian M, et al. Tear ascorbic acid levels and the total antioxidant status in contact lens wearers: a pilot study. Indian journal of ophthalmology. 2009;57(4):289-92. Epub 2009/07/04.
Coral K, Angayarkanni N, Gomathy N, Bharathselvi M, Pukhraj R, Rupak R. Homocysteine levels in the vitreous of proliferative diabetic retinopathy and rhegmatogenous retinal detachment: its modulating role on lysyl oxidase. Investigative ophthalmology & visual science. 2009;50(8):3607-12. Epub 2009/04/17.
Angayarkanni N, Selvi R, Pukhraj R, Biswas J, Bhavesh SJ, Tombran-Tink J. Ratio of the vitreous vascular endothelial growth factor and pigment epithelial-derived factor in Eales disease. Journal of ocular biology, diseases, and informatics. 2009;2(1):20-8. Epub 2010/01/15.
Jayachandran VV AN, Coral K et al. Diffusion of lidocaine buffered to an optimal pH across the endotracheal tube cuff – an in vitro studies Indian J Anaesth. 2008;52)5):536-40.
Coral K, Angayarkanni N, Madhavan J, Bharathselvi M, Ramakrishnan S, Nandi K, et al. Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachment. Investigative ophthalmology & visual science. 2008;49(11):4746-52. Epub 2008/06/21.
Angayarkanni N, Barathi S, Seethalakshmi T, Punitham R, Sivaramakrishna R, Suganeswari G, et al. Serum PON1 arylesterase activity in relation to hyperhomocysteinaemia and oxidative stress in young adult central retinal venous occlusion patients. Eye (Lond). 2008;22(7):969-74. Epub 2007/12/18.
Selvi R, Angayarkanni N, Bharathselvi M, Sivaramakrishna R, Anisha T, Jyotirmoy B, et al. Increase in Fe3+/Fe2+ ratio and iron-induced oxidative stress in Eales disease and presence of ferrous iron in circulating transferrin. Current eye research. 2007;32(7-8):677-83. Epub 2007/09/14.
Ramakrishnan S, Rajesh M, Sulochana KN. Eales' disease: oxidant stress and weak antioxidant defence. Indian journal of ophthalmology. 2007;55(2):95-102. Epub 2007/02/27.
Narayanasamy A, Subramaniam B, Karunakaran C, Ranganathan P, Sivaramakrishnan R, Sharma T, et al. Hyperhomocysteinemia and low methionine stress are risk factors for central retinal venous occlusion in an Indian population. Investigative ophthalmology & visual science. 2007;48(4):1441-6. Epub 2007/03/29.
Madhavan J, Coral K, Mallikarjuna K, Corson TW, Amit N, Khetan V, et al. High expression of KIF14 in retinoblastoma: association with older age at diagnosis. Investigative ophthalmology & visual science. 2007;48(11):4901-6. Epub 2007/10/27.
Barathi S, Vadhana P, Angayarkanni N, Ramakrishnan S. Estimation of hydrogen sulphide in the human lymphocytes. Indian journal of biochemistry & biophysics. 2007;44(3):179-82. Epub 2007/07/27.
Angayarkanni N, K.Coral, SR. Bharathidevi, A chapter on “Toxicology,” in Dr. Santhanam’S Text book of occupational optometry , First Edition, SN, 2015 pp 219-39.
Angayarkanni N, K.Coral, SR. Bharathidevi , Ocular biochemistry chapter in “Pharmacology of Ocular Therapeutics”e, Springer Publications , 2015
Saravanan R and Sulochana KN. Oxidative Stress in Eales Disease. An Update. Chapter in the book published by NOVA “ oxidative stress in Diseases” 2014
Ramakrishnan S, Sulochana KN. Manual of Medical Laboratory Techniques” Chapter in clinical Biochemistry from Jaypee brothers, (Laboratory Book) 2012.
Sulochana KN, Coral K. Extra cellular matrix protein, Lysyl oxidase, as a therapeutic target for ocular angiogenesis” In: Advances in Medicine and Biology. Vol.1(Chapter 15) Editor: Leon V. Berhardt. 2009 Nova Science Publishers, Inc
Ramakrishnan S, Angayarkanni N. Basics in Biochemistry for Professional Nursing. BI Publications Pvt Ltd. 2007.