| I. |
To evaluate the in vitro efficacy of PLGA-nanoparticles encapsulated with chemotherapeutic drugs to induce apoptosis in Y79 retinoblastoma cell line
|
| |
The project is useful in studying the invitro efficacy of PLGA nanoparticles encapsulated with chemotherapeutic drugs(etoposide, doxorubicin, vincristine) to induce apoptosis in Y79 retinoblastoma cell line.
|
| II. |
Efficacy of EpCAM-conjugated drug loaded biodegradable nanoparticles for drug therapy in Retinoblastoma
|
| |
This project helps in studying the efficacy of Epcam antibody conjugated drug loaded biodegradable Nanoparticles for drug therapy in Retinoblastoma cell line.
|
| III. |
Developing Molecularly targeted polymer Nanoparticles for cancer diagnostics and Therapeutics.
|
| |
This project is about to make a novel aptamer against EpCAM molecule which is found to be over expressed in majority of epithelial careers including retinoblastoma. This aptamer should block functional property of EpCAM.
|
| IV. |
HMGA2 gene is a promising target for therapy in Retinoblastoma by RNA Interference
|
| |
In this study, we have proposed to work on the silencing of the HMGA2 gene, which would enable us to identify it as the promising target to combat retinoblastoma.
|
| V. |
“Phase I Clinical trial: Sub-conjunctival in Fibrin Sealant in Patients with Advanced retinoblastoma”
|
| |
This project is used to study the maximum tolerated dose of carboplatin in fibrin sealant in Indian children with retinoblastoma.
|
| VI. |
To investigate the effect of Tiam1 siRNA on Tumor cell survival and proliferation in Retinoblastoma.
|
| |
This project is used to study the molecular mechanisms that lead to invasiveness in retinoblastoma tumors and to rule out preventive and therapeutic strategies. |
